It is not prescribed for cats that are: It may lead to some drug interactions if used along with P-glycoprotein inhibitors including Ivermectin and other macrocyclic lactones, cyclosporine, prednisolone, and erythromycin [10, 11]. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Remove one unit dose tube from the package. The necropsy showed chronic active cholangiohepatitis. Dose Tolerance Study in Cats: PROFENDER Topical Solution was applied topically one time to young cats at 10X the recommended label use rate.

Not for human use. In rare cases, the drug can trigger vomiting and diarrhoea. However, in some cases, a cat who licks the application site may suffer more severe side effects than a cat who does not. Treatment at the base of the head will minimize the opportunity for ingestion while grooming. Regulations for product use are established by country. Data from these studies demonstrated PROFENDER Topical Solution is safe and effective for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults). For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Break the tube’s seal, part your cat’s hairs, and then apply by squeezing the entire content onto the skin behind its neck [3].

In case of accidental ingestion or if skin or eye irritation occurs, call a poison control center or physician for treatment advice.

No side effects have been reported in dogs.

Topical Solution for the treatment and control of hookworm, roundworm and tapeworm infections in cats and kittens that are at least 8 weeks of age and weigh at least 2.2 lbs (1 kg). However, these occur in rare cases and usually go away without further treatment [1].

Temporary effects like a damp appearance or stiffening of the hair, and a powdery residue may be seen at the site of application [9]. These effects are temporary and do not affect the safety or effectiveness of the product. Stiff hair, a damp appearance of the hair, or a slight powdery residue may be observed at the treatment site. Pet owners deal with scratches. Post-Approval Experience: The following adverse events are based-on post-approval adverse drug experience reporting. In most cases, a single dose may effectively control the infection [3]. The Material Safety Data Sheet (MSDS) provides additional occupational safety information. In rare cases, the drug can trigger vomiting and diarrhoea. Although he grew up in Latin America, Mr. Ma is a writer based in Denver. Patents: 5 514 773 and other patents pending. In some cases, death has been reported as an outcome of the adverse events listed. Every effort has been made to ensure the accuracy of the Profender (emodepside/praziquantel) Topical Solution information published above. Some cats will lick or groom excessively. For a complete listing of adverse reactions for Profender Topical Solution reported to the CVM see: http://www.fda.gov/ADEreports. The effectiveness of this product when used before bathing has not been evaluated.

In yet other cases, you may see a cat with shaking and tremors because of this drug.

Profender is usually cautiously used in pregnant, nursing, or debilitated cats [6]. Clinical signs included salivation (one 1X and three 5X cats), labored breathing (all groups) and lethargy (one 5X cat). For customer service or to obtain product information, including the MSDS, call 1-800-633-3796.

In households with multiple pets, keep animals separated to prevent licking of the application site. The cats exhibited salivation, vomiting, tremors, abnormal gait, abnormal respiration and weight loss. 6. Foreign Market Experience: The following adverse events were reported voluntarily during post-approval use of the product in foreign markets: application site reaction (hair loss, dermatitis, pyoderma, edema, and erythema), salivation, pruritus, lethargy, vomiting, diarrhea, dehydration, ataxia, loss of appetite, facial swelling, rear leg paresis, seizures, hyperesthesia, twitching, and death. Safe use of this product has not been evaluated in cats less than 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy or in lactating queens. Avoid its use on broken skin or wet coat [3], and make sure not to get the medicine in your cat’s eyes or mouth [6]. Plus, if the cat didn't take all the medication, you remain unsure that enough medicine was swallowed to kill off the worms. 82482521/03615026/82482572/03615034/82482580/82482602, R.2. Safety Study in Heartworm Positive Cats: Cats artificially infected with adult heartworms harvested from dogs were treated topically with PROFENDER Topical Solution at 0X, 1X or 5X the recommended dose once a month for three treatments.

Talk to the vet about any precautions to take while applying Profender. The physical side effects of Profender include hair loss and excessive salivation. The listing includes Adverse Events reported to CVM for products, such as Profender, that contain the combined active ingredients emodepside and praziquantel. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. In other cases, Profender can cause a cat to become lethargic. cats image by Zbigniew Nowak from Fotolia.com. In some cases, you may notice eye and respiratory irritation. Adverse reactions reported by the cat owners included licking/ excessive grooming in 18 cats (3.0%), scratching treatment site in 15 cats (2.5%), salivation in 10 cats (1.7%), lethargy in 10 cats (1.7%), alopecia in 8 cats (1.3%), agitation/nervousness in 7 cats (1.2%), vomiting in 6 cats (1.0%), diarrhea in 3 cats (0.5%), eye irritation in 3 cats (0.5%), respiratory irritation in 1 cat (0.2%) and shaking/tremors in 1 … Select one or more newsletters to continue. Reactions such as facial, tongue and hand swelling have been reported in humans in rare instances. Adverse reactions reported by the cat owners included licking/excessive grooming in 18 cats (3.0%), scratching treatment site in 15 cats (2.5%), salivation in 10 cats (1.7%), lethargy in 10 cats (1.7%), alopecia in 8 cats (1.3%), agitation/nervousness in 7 cats (1.2%), vomiting in 6 cats (1.0%), diarrhea in 3 cats (0.5%), eye irritation in 3 cats (0.5%), respiratory irritation in 1 cat (0.2%) and shaking/tremors in 1 cat (0.2%). Flattie V (AKA my flat self, AKA my visual foam standin) got to chat with two Bayer representatives at the May 2017 BlogPaws Conference about Profender for cats, a topical dewormer.Mom has used this treatment on me on more than one occasion to rid me of tapeworms. Two cats salivated.



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